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CPID

Health effects of consumer products

Roc Retinol Actif Pur Anti-Wrinkle Treatment Day

• Chemical Composition/Ingredients

  The GHS is an acronym for The Globally Harmonized System of Classification and Labelling of Chemicals. The GHS is a system for standardizing and harmonizing the classification and labelling of chemicals. Chemicals are associated with codes that define their health, physical and environmental hazards.This universal hazard communication system was developed to ensure that employers, employees and consumers are provided with adequate, practical, reliable and comprehensible information on the hazards of chemicals, so that they can take effective preventive and protective measure for their own health and safety.
  The GHS classifications for chemicals associated with products in this database may be viewed by selecting the "Advanced" button on the Chemical Ingredients tables. Since this is a work in progress, GHS classifications may not be shown for all chemical ingredients.

  Advanced
  Primary Chemical Name is the standard name assigned to a chemical substance. Chemical	Chemical Abstracts Service Registry Number is a unique identifier for a chemical and its synonyms. CAS numbers identify the chemical, but not its concentration or specific mixture.  CAS Registry Numbers are assigned by the Chemical Abstracts Service, a division of the American Chemical Society. For more information: www.cas.org We have assigned "ID numbers" (with 6 leading zeros or nines, e.g., 000000-xx-x , 888888-xx-x) or 999999-xx-x) for blends and chemicals that do not have CAS numbers.  CAS No./ID	Percent of chemical in preparation. % Conc.		Chemical of Concern (CoC) Chemical of Concern(CoC)
  Water	007732-18-5	>50		No
  Glycerin	000056-81-5	1.0-5.0		No
  Alkyl (C12-15) benzoate	068411-27-8	5.0-10.0		No
  Ethylhexyl Methoxycinnamate	005466-77-3	5.0-10.0		Yes  ME-01-Maine Chemicals of High Concern (CHC) MN-01-Minnesota Toxic Free Kids, CHC OR-01: Oregon HPCCCH VT-01: Vermont State CHCC WA-01: Washington State CHCC  CoC List
  Avobenzone	070356-09-1	1.0-5.0		No
  Lactose	000063-42-3	--		No
  Glyceryl polymethacrylate	999999-90-4	--		No
  Butylene glycol	000107-88-0	--		No
  Talc (non-fibrous)	014807-96-6	--		Yes  NY-01: California Prop. 65 Chemical NY-08: IARC Group 1, 2A & 2B Carcinogens CA-01-California Prop. 65 Chemicals CA-09-IARC Group 1, 2A & 2B Carcinogen  CoC List
  Aluminum starch octenylsuccinate	009087-61-0	--		No
  2-Phenoxyethanol	000122-99-6	--		No
  Tocopheryl acetate	007695-91-2	--		No
  Poloxamer-407	977057-91-2	--		No
  Acrylates/C10-C30 Alkyl acrylate crosspolymer	000000-50-3	--		No
  Methylparaben	000099-76-3	--		Yes  NY-20:CA Environmental Biocontaminant Monitoring Program Priority Chemical NY-29: Short List Of Chemicals of Concern CA-21-California Environmental Biocontaminant Monitoring Program Priority Chemicals CA-23-Nonfunctional Constituents ME-01-Maine Chemicals of High Concern (CHC) MN-01-Minnesota Toxic Free Kids, CHC OR-01: Oregon HPCCCH VT-01: Vermont State CHCC WA-01: Washington State CHCC  CoC List
  Disodium EDTA	000139-33-3	--		No
  Sodium dehydroacetate	004418-26-2	--		No
  Carbomer	009003-01-4	--		No
  2,6-Di-t-butyl-p-cresol (BHT)	000128-37-0	--		Yes  MN-01-Minnesota Toxic Free Kids, CHC  CoC List
  Isopropylparaben	004191-73-5	--		No
  Propylene glycol	000057-55-6	--		Yes  NY-11: NTP Reproductive or Developmental Toxicant NY-26: New York DOH MCL CA-12-NTP Reproductive or Developmental Toxicants  CoC List
  Sodium methylparaben	005026-62-0	--		No
  PEG-80 sorbitan laurate	009005-64-5	--		No
  Retinol (Vitamin A)	011103-57-4	--		No
   
  Click on each chemical for information on chemical structure, properties and health effects.
  Click on Chemical, CAS No./ID headings to sort values.
  

  Primary Chemical Name is the standard name assigned to a chemical substance.

  Chemical

  Chemical Abstracts Service Registry Number is a unique identifier for a chemical and its synonyms. CAS numbers identify the chemical, but not its concentration or specific mixture.  CAS Registry Numbers are assigned by the Chemical Abstracts Service, a division of the American Chemical Society. For more information: www.cas.org
  
  We have assigned "ID numbers" (with 6 leading zeros or nines, e.g., 000000-xx-x , 888888-xx-x) or 999999-xx-x) for blends and chemicals that do not have CAS numbers. 

  CAS No./ID

  Is a seven-digit number (xxx-xxx-x) assigned by the European Commission to chemicals contained in three inventories:
  EINECS is the European Inventory of Existing Commercial Substances and its EINECS numbers are displayed as 2xx-xxx-x.
  ELINCS is the European List of Notified Chemical Substances that was available after September 18, 1981 and its ELINCS numbers are displayed as 4xx-xxx-x.
  NLP is the No-Longer Polymers category and its NLP numbers are displayed as 5xx-xxx-x

  EC No.

  Percent of chemical in preparation.

  % Conc.

  The GHS is an acronym for The Globally Harmonized System of Classification and Labelling of Chemicals. The GHS is a system for standardizing and harmonizing the classification and labelling of chemicals. Chemicals are associated with codes that define their health, physical and environmental hazards.This universal hazard communication system was developed to ensure that employers, employees and consumers are provided with adequate, practical, reliable and comprehensible information on the hazards of chemicals, so that they can take effective preventive and protective measure for their own health and safety.
  The GHS classifications for chemicals associated with products in this database may be viewed by selecting the "Advanced" button on the Chemical Ingredients tables. Since this is a work in progress, GHS classifications may not be shown for all chemical ingredients.

   UN Global Harmonization Classification

  Hazard Codes and their associated descriptions are an essential part of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). There are 4 categories of Hazard Codes:

  • Physical Hazard Codes (H200 series)
  • Health Hazard Codes (H300 series)
  • Environmental Hazard Codes (H400 series)
  • Supplementary Hazard Codes (EUH series)

  Hazard Codes may be found in the "Advanced" version of Chemical Composition / Ingredients tables.

  Hazard Statement Code

  Precautionary Codes and their associated descriptions are an essential part of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
  Precautionary Codes may be found in the "Advanced" version of Chemical Composition / Ingredients tables.

  Precautionary Code

  Pictogram

  SVHC is a substance (identified by the European Chemicals Agency) that may have serious and often irreversible effects on human health and the environment. SVHC are defined in Article 57 of Regulation (EC) No 1907/2006 (“the REACH Regulation”) and include substances which are:
  1.  Carcinogenic, Mutagenic or toxic to Reproduction (CMR), meeting the criteria for classification in category 1 or 2 in accordance with Directive 67/548/EEC or in category 1a or 1b in accordance with EC No 1272/2008This directive was recently replaced by the new EU regulation (EC) No 1272/2008.
  2.  Persistent, Bioaccumulative and Toxic (PBT) or very Persistent and very Bioaccumulative (vPvB) according to the criteria in Annex XIII of the REACH Regulation, or
  3.  Identified, on a case-by-case basis, from scientific evidence as causing probable serious effects to human health or the environment of an equivalent level of concern as those above (e.g. endocrine disrupters).

  SVHC?

  Water	007732-18-5	231-791-2	>50	-------- ------- ---- No
  Glycerin	000056-81-5	200-289-5	1.0-5.0	-------- ------- ---- No
  Alkyl (C12-15) benzoate	068411-27-8	270-112-4	5.0-10.0	-------- ------- ---- No
  Ethylhexyl Methoxycinnamate	005466-77-3	226-775-7	5.0-10.0	-------- ------- ---- No
  Avobenzone	070356-09-1	274-581-6	1.0-5.0	-------- ------- No
  Lactose	000063-42-3	200-559-2	--	-------- ------- ---- No
  Glyceryl polymethacrylate	999999-90-4	--	--	-------- ------- ---- No
  Butylene glycol	000107-88-0	203-529-7	--	-------- ------- ---- No
  Talc (non-fibrous)	014807-96-6	238-877-9	--	-------- P101, P102, P280, P305+P351+P338 ---- No
  Aluminum starch octenylsuccinate	009087-61-0	-	--	-------- ------- ---- Yes
  2-Phenoxyethanol	000122-99-6	204-589-7	--	H302, H319 P264, P280, P330, P337+P313, P305, P351, P338 No
  Tocopheryl acetate	007695-91-2	231-710-0	--	-------- ------- ---- No
  Poloxamer-407	977057-91-2	--	--	-------- ------- ---- No
  Acrylates/C10-C30 Alkyl acrylate crosspolymer	000000-50-3	--	--	-------- ------- ---- No
  Methylparaben	000099-76-3	202-785-7	--	H411 P273, P391, P501 No
  Disodium EDTA	000139-33-3	205-358-3	--	-------- ------- ---- No
  Sodium dehydroacetate	004418-26-2	224-580-1	--	H302 P301+P312 No
  Carbomer	009003-01-4	618-347-7	--	H302, H318, H335, H400, H411 P261, P270, P271, P280, P305+P351+P338, P310, P330, P304+P340, P273 No
  2,6-Di-t-butyl-p-cresol (BHT)	000128-37-0	204-881-4	--	H410 ------- No
  Isopropylparaben	004191-73-5	224-069-3	--	H317, H315, H319 ------- No
  Propylene glycol	000057-55-6	200-338-0	--	-------- ------- ---- No
  Sodium methylparaben	005026-62-0	225-714-1	--	H318, H315, H412 P280, P264, P305+P351+P338, P302+P352, P310, P362, P273, P501 No
  PEG-80 sorbitan laurate	009005-64-5	500-018-3	--	-------- ------- ---- No
  Retinol (Vitamin A)	011103-57-4	--	--	-------- ------- ---- No

   

  Click on each chemical for information on chemical structure, properties and health effects.
  Click on Chemical, CAS No./ID or EC No. headings to sort values.
  

   

  Sources for Chemical Classifications

  • European Commission>JRC>IHCP>European chemical Substances Information System (ESIS) Table 3.1
  • European Chemicals Agency, http://echa.europa.eu/
       ECHA Disclaimer: http://echa.europa.eu/web/guest/legal-notice
• • Health Effects Information

    • Ingredients and Health Effects Information are taken from the manufacturer's product label and/or the Material Safety Data Sheet (MSDS). Products are not tested and manufacturer's information presented here is not evaluated by DeLima Associates.

    • Date that Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) was issued by manufacturer of product. MSDS DATE :

      November 20, 1999

    • 	Health	Flammability	Reactivity
      HMIS is the Hazardous Materials Identification System developed by the American Coatings Association and indicates the levels (“1” to “4”) of Health Hazard, Flammability Hazard and Physical Hazard associated with a specific product. HMIS RATING	N	N	N

    • Warnings

      Warning: For external use only. Keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash or irritation develops and lasts. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center.

    • Acute health effects

      From MSDS Primary Route(s) of Entry Eyes - May cause eye irritation Skin - No effects expected. Ingestion - No effects expected under normal handling conditions; i.e., dispensing and administering liquid. Inhalation - No effects expected from normal handling of liquid outside of package. Medical Conditions Aggravated by Exposure - In case of accidental overdose, contact a Physician or Poison Control Center. Toxicological Information Acute Studies - Unknown Eye Effects - Unknown Skin Effects - No significant reactions have been observed in clinical testing for irritation, allergenicity, phototoxicity, and photoallergenicity.

    • Chronic health effects

      From MSDS None known.

    • Carcinogenicity

      From MSDS Unknown

    • Handling information

      From MSDS Keep from freezing. This product should be handled and stored per label instructions to ensure product integrity.

    • Disposal information

      From MSDS Ensure compliance with local, state, and federal regulations.

    • First Aid

      From MSDS Eyes - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Skin - Get medical attention if irritation develops or persists. Ingestion - If swallowed, seek medical advice immediately and show the package container or label. Inhalation - If symptoms develop obtain medical attention.